North Texas will be down three key players when it opens its season Friday with a home game against Mid-America Christian.
Tyara Warren has elected to end her career due to a knee injury, while Madison Townley and Hannah Hopkins are out for the season with injuries.
UNT coach Jalie Mitchell confirmed the players' status Tuesday.
"It's a big hit," Mitchell said. "Our freshmen are going to have to show up and our returners are going to have to play a bigger role. It's part of it, unfortunately."
Warren, who averaged 7.5 points last season, has an anterior cruciate ligament that is frayed and would require surgery if she continued playing.
Townley has undergone shoulder surgery and will redshirt this season after averaging 2.3 points and 3.8 rebounds as a freshman. Hopkins tore the ACL in her knee over the summer.
UNT enters the season off a 12-19 campaign that included a win over UAB in the opening round of the Conference USA tournament.
BRETT VITO can be reached at 940-566-6870 and via Twitter at @brettvito.
FEATURED PHOTO: North Texas guard Tyara Warren drives to the basket as Western Kentucky forward Tashia Brown (10) defends at the Super Pit. Warren has given up basketball due to a knee injury and is one of three players UNT will be without when it opens the season on Friday. (Jeff Woo/DRC)